Hydroxypropyl Methyl Cellulose pharmaceutical grade is widly used for vegetarian capsule, coating, adhesive and so on.
Hydroxypropyl Methyl Cellulose HPMC
1.Brief Introduction
is multi purpose medicinal materials can be used as thickener, dispersant, emulsifier and film-forming agent. Made in the drug tablet film coating, adhesive.can improve the dissolution rate of drugs can enhance the waterproof tablets. Also as a suspension, ophthalmic preparations, controlled release formulations such as skeletons and floating tablets. HPMC and other synthetic polymers and colloidal drug binding, can prevent water and alcohol drugs from the transparent gel to separate the water and improve water retention, is also being food, cosmetics and other areas used as a thickener, emulsifier and improve Rheological properties, as well as to other daily-use chemical industry, etc. Currently this product has become the main material for plant capsule.
Comply with USP, EP and CP
2.Technical Specification
Item | Grade | ||
E_PH(2910) | F_PH(2906) | K_PH(2208) | |
Methoxy(WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropox(wt%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Gelation temperature(°C) | 58.0-64.0 | 62.0-68.0 | 70.0-90.0 |
Viscosity(mPa.s)(2% solu., 20°C) | 3,5,6,15,50,4000 | 50,4000 | 100,4000,15000,100000 |
Loss on drying(%) | ≤5.0 | ||
Residue on ignition(%) | ≤1.5 | ||
pH | 44.0-8.0 | ||
Heavy Metals(ppm) | ≤20 | ||
Arsenic(ppm) | ≤2.0 | ||
3. Application suggestion
Specification | Reference dosage(%) | Advantages | Applications |
E3PH E5PH E6PH E15PH | 0.5-5 | Water or water used for organic solvent coating, excellent film forming and viscosity, have good barrier, an increase of compressive strength, reduction of debris . | Coating |
1-5 | Mixed with Ethyl Cellulose used as a coating of organic solvent to form a solid, with good adhesive film, a masking role of smell. | Coating | |
E5PH E6PH E15PH | 3-20 | Control released cotaing, Mixed with Ethyl Cellulose regulate proliferation. | Control released agent |
E15PH E50PH | 2-6 | On the suspended solid particles have a good performance of lubrication and thickening Low concentration, high hardness, low friability and good disintegration properties, production pressure when the machine is small, extended equipment life. | Granulation, lablet, binder |
E15PH E4000PH | 1-2 | On the suspended solid particles have a good effect and good anti-microbial properties | Antacid |
E50PH E4000PH | 0.1-0.5 | Solution of high clarity, low concentrations have a good performance of lubrication and thickening | Eyedrop |
E4000PH | 1-2 | The role of suspended solids | Suspending agent |
E4000PH K4000PH | 1-5 | Protective effects of colloidal and emulsifying properties of the liquid drug preparation of favor | Emulsions, gels and ointments |
5-30 | Aperient |
Hydroxypropyl Methyl Cellulose HPMC
