Can be used as a refrigerant, it is the important component of mixed refrigerant, used as a substitute for CFC-502 and HCFC-22; HFC-125 is an important component of mixed working medium. It can be refrigerant for replacing CFC-502 and HCFC-22.HFC-125 also can be used as extinguishant for replacing Halon-1211 and Halon-1301. HFC-125 refrigerant