... used widely in both the pharmaceutical and food industries, such as encapsulating agents, adhesives, thickening, and extending agent. Pullulan ... over 20 years in Japan. It has Generally Regarded As Safe (GRAS) status in the US for a much wider ... and sales of green food additives ,cosmetics as well as crude drug products, such as biological polysaccharides, preservatives, and macromolecule polymers. ...