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pharmaceutical grade Pullulan
pharmaceutical grade Pullulan

1 pharmaceutical grade Pullulan 2 non-toxic, non-mutagenic, odorless, tasteless, and edible.

PULLULAN

KOSHER 

HALAL    

ISO 9000  

Introduction

    Pullulan is natural water-soluble polysaccharide, produced from starch by fermentation. It is a linear, neutral glucan consisting mainly of maltotriose units linked through α-1, 6 - glucosidic bonds. Pullulan is an extremely versatile ingredient providing a technology platform for product innovation. It is an excellent film-former, producing a film which is heat sealable with good oxygen barrier properties and which can also be printed. It can be used widely as thickening or extending agents and adhesives or encapsulating agents, in food and pharmaceutical industry.

Pullulan has been used as a food ingredient for over 20 years in Japan. It has Generally Regarded As Safe (GRAS) status in the US for a much wider range of applications and thus higher intakes than the current application.

Molecular formula

 (C6H10O5)x 

Properties

Pullulan is non-toxic, non-mutagenic, odorless, tasteless, and edible. Dry pullulan powders are white and non-hygroscopic and dissolve readily in hot or cold water. Pullulan solutions are of relatively low viscosity. The viscosity of pullulan solutions is stable to heating, changes in pH, and most metal ions, including sodium chloride.

Applications

Pullulan can be used as either an innovative or decorative film or used in granule form for:

 Tabletting: Pullulan is an excellent tabletting excipient.

 Pan coating: Pullulan with its excellent adhesive properties and extremely low viscosity is ideally suited for pan-coating chewing gum, chocolate and candies.

 Agglomeration: Pullulan has about double the adhesive strength of food starch. This property combined with its lack of flavor enables it to be used effectively in typical agglomeration processes.

 Sauces and dressings: Due to its ‘adhesive properties’ use of granular pullulan in sauces improves their ‘on product’ retention without unduly increasing sauce viscosity.

 Innovative soft candy: Incorporation of 2-3% Pullulan, enables innovative soft chewy candies to be made by a cold extrusion process without resorting to conventional boiling. This enables heart sensitive materials to be used in these products.

  Coatings: Pullulan solutions which are odorless and flavorless can be used as a coating for a wide range of food products to improve appearance, reduce blemishes and increase shelf life.

 Capsules: Pullulan can be formed into capsules for use with pharmaceutical and nutraceutical products. Its non-animal origin ensures there are no safely concerns with consumers and it is suitability for all consumers groups.

Product Specification

Solubility

 Soluble in water, practically insoluble in ethanol

pH

5.0 - 7.0 (10% solution)

Loss on drying

Not more than 6% (90°, pressure not more than 50 mm Hg, 6 h)

Mono-, di- and oligosaccharides

Not more than 10% (expressed as glucose)

Viscosity

100-180 mm2/s (10% w/w aqueous solution at 30°)

Lead

Not more than 1 mg/kg.

Microbiological criteria

Yeast and moulds: Not more than 100 CFU/gColiforms: Negative in 25 gSalmonella: Negative in 25 g

Packing and storage

  500g/bottle, 10kg/carton, 25 kg/carton or packed to customer’s requirement.

  Keeping in cool place with no direct sunshine exposure and the temperature is below 20°C, the validity period is two years.

Patents

CN 200810187281.0 A mask containing pullulan.

pharmaceutical grade Pullulan

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