1.High water solubilty 2.High bioavailability 3.High drug loading 4.Low excipents amount 5.Use novel nanotechnology
Water-soluble Coenzyme Q10
Water-soluble Coenzyme Q10 is prepared with a novel nanotechnology, which does not change the chemical structure of Coenzme Q10, but greatly improve its water solubility and oral bioavailability. This product can be easily added to a variety of functional foods or cosmetics.
1. Description
Pale yellow to yellow oily liquid, miscible with water or alcohol in any ratio.
2. Specifications / (Content of Coenzyme Q10)
5%(W/W), 10%(W/W), 15%(W/W)
3. Storage
Dried at room temperature, protected from light.
4. Features
* High water solubility: Miscible with water in any ratio to form a clear and transparent microemulsion with particle size less than 100nm.
* High drug loading: Content of coenzyme Q10 can be as high as 15% by mass percentage in this product.
* High bioavailability: Water-soluble product can increase the oral bioavailability of coenzyme by more than 5 times.
* Low excipients amount: Compared to the traditional microemulsion, this product use completely biocompatible materials and minimizes the amount of surfactant.
5. Effects
* Health food
Heart protection:Effectively relieve myocardial ischemia, prevention of sudden cardiac.
Relieve fatigue: An important participant in cell electronics chain transfer to maintain cell viability.
Strengthening the immune system: Endogenous natural antioxidant, prevent the formation of free radicals, helps maintain the normal functioning of the immune system and aging.
Other effects: Help patients with cancer or hyperlipidemia to maintain health.
* Cosmetics
Skin protection: Weaken the photon oxidation reaction in skin growth layer, delay of skin aging;
Retain moisture: Strengthen cell metabolism, revive the tight junctions between cells;
* Application
Healthy food industry
Cosmetics industry
NNET: Novel Nano Emulsion Technique
A nano-emulsion preparation technique with the aid of analytical techniques and computer design, selects the method of self-emulsifying or physical homogeneous to produce water-soluble preparation of insoluble compounds as well as protect and increase its bioactivity in oral route.
NNET with self-emulsification
NNET with physical homogeneous
As a technology used in health care and food industry, NNET platform has the following significant advantages:
*Simple excipients and concise process.
*Effectively improve the oral absorption while improve the water-solubility.
*Effectively maintain the biological activity of the raw materials.
*Complete with safety excipients.
CERTIFICATE OF ANALYSIS
Product Name | Water-soluble coenzyme Q10 | Content (w/w) | 10% | ||
Batch No. | Batch size | Mfg. Date | Exp. Date | Report Date | Standard |
20120521 | 10 kg | 20120521 | 20140520 | 20120522 | Enterprise Standard |
Items | Specification | Result |
Appearance | orange-yellow liquid, odorless | Conforms |
Solubility | Arbitrary proportion of mixed with water,no precipitation, layered or other turbid phenomena occur. | Conforms |
Identification | Dissolve 20g Water-soluble coenzyme Q10 in 100ml water and mix. Add 50mg sodium borohydride and mix: the yellow color disappears. | Conforms |
Heavy metals | No more than 20ppm | 5ppm |
Related substances Isomer | Isomer peak area is not more than 0.5% of the main peak area. | 0.1% |
Microbial limits Total Aerobic Microbial Count Total Yeast and Mold Count E. coli Staphylococcus aureus Salmonella | Max. 104 CFU/g Max. 100CFU/g Negative in 10g Negative in 10g Negative in 10g | <104 CFU/g <100 CFU/g Negative Negative Negative |
Assay | Does not exceed the labeled amount of 90% -110% | 98.5% |
Beijing Wisapple Biotech Co., Ltd is co-founded by Beijing Z&T investment corporation and an eminent professor in Tsinghua University, dedicated in the development, production and distribution of raw-materials and finished products in the field of food supplement, functional food and bio-medicine.
1.R&D
Leading by CAS academician, a scholastic committee is found by experts, professors and industry professionals to guide our R&D.
Over ten PhD and Master form up the development team to investigate into the new formulation application for fulfilling the demands of market.
A multi-million research center in the facility is proven to provide a comprehensive research and assay service for all customers.
2.Production and Quality
An ICH GMP designed factory with over 10,000 square meters and with 100,000 grade clean area is constructed to provide in-time production.
Experienced QA and QC team and advanced testing instruments enable us to a high quality assurance for every customer.
3.Sales
A international trading team is specialized in the field of bio-medicine and dietary supplement, aiming to forge a novel distribution system to guarantee a systematic service experience for our customers.
Our trade show on CPHI Shanghai
water soluble Co Q10 product (Novel Nano Emulsion Technique)