Papain/papayotin /nematolyt Botanical Resource: Chaenomeles sinensis or Chaenomeles speciosa Chinese Name Mu Gua Family Chaenomeles Part of the Plant Used Fruit Active Ingredients Papain Product Specification Papain 50,000 u/g to 3,500,000 u/g or 60TU/mg-1750TU/mg Papain Coarse-enzyme: >50,000 u/g Papain Sub-enzyme: > 1,000,000 u/g Refined Papain: > 2,300,000 u/g High-activity Refined Papain: > 3,000,000 u/g Applications 1.Medical Application: can help ease swelling, alleviate inflammation, improve immunity, promote digestion and diminish intestinal parasite. 2.Food and food additive: the papain can be made into tenderizer for meat, purifying agent for beer and softener for biscuits, producing dehydrated beans, food for babies, cheese and 3.oncondensing oleo oil 4.Leather Industry: The papain can be made into depilatory for tanning the leathers, making the products smooth and shiny. 5.Cosmetics: The papain can help dispel taches ad pimples, clean you face, promoting the blood circulation, making you skin healthier and tender. 6.Brewing industry etc. 7.The crude papain is used in the brewing industry for chillproofing beer and lager and the enzyme serum is a very excellent for wort clarificant. Uses：Papain breaks down tough meat fibres, and has been used for thousands of years to tenderise meat eaten in its native South America. Meat tenderisers in powder form with papain as an active component are widely sold. Papain can be used to dissociate cells in the first step of cell culture preparations. A ten-minute treatment of small tissue pieces (less than 1 mm cubed) will allow papain to begin breaking down the extracellular matrix molecules holding the cells together. After ten minutes, the tissue should be treated with a protease inhibitor solution to stop the protease action (if left untreated, papain's activity will lead to complete lysis of the cells). The tissue must then be triturated (passed quickly up and down through a Pasteur pipette) to break up the pieces of tissue into a single cell suspension. It is also used as an ingredient in various enzymatic debriding preparations, notably Accuzyme. These are used in the care of some chronic wounds to clean up dead tissue. Papain is also used in some toothpastes and mint sweets as a tooth whitener; however, its whitening effect is minimal, because the papain is present in low concentrations and is quickly diluted by saliva. It would take several months of use, to have a noticeable effect. It is the main ingredient of Papacarie, a gel used for chemomechanical dental caries removal. It does not require drilling and does not interfere in the bond strength of restorative materials to dentin. Papain has been known to interfere with urine drug tests for cannabinoids.It is found in some drug detox products.
