Sinoway Industrial Co.,Ltd is a famous China tacrolimus manufacturer and supplier,Website:http://www.sinoway-chem.com, welcome to buy GMP and EP tacrolimus from us and check the price with us.Basic information ofTacrolimus:NameTacrolimus (FK506)CAS :104987-11-3Molecular FormulaC44H69NO12·H2OMolecular Weight822.04QualityStandardIn-house Standard, Assay: >99.0% / USP36Package SizeAluminium bag; Weight: Net weight 50g/bag and 100g/bagBrief IntroductionTacrolimus is a macrolideimmunosuppressant produced by Streptomyces tsukubaensis. Tacrolimus is used toprevent rejection of organtransplants. Tacrolimus is 10 to 100 times superior to cyclosporin in improving graft survival and preventing acuterejection after transplantation, but decreasing the toxinside effects.Use of Tacrolimus:1)Anti-rejection in organ transplantation2) Treatment of skin diseases.likeatopicdermatitis(AD),systemic lupus erythematosus(SLE),autoimmuneeye diseaseand other autoimmune diseasesCOA ofTacrolimus:TestsSpecificationsResultsDescriptionAwhiteoroff-whitecrystallinepowderConformIdentification1.IR(USP<197K>)Conform2.HPLCretentiontimesConformWater(USP<921>MethodI)1.6~3.0%2.1%Residueonignition(USP<281>)£0.2%0.08%Heavymetals(USP<231>II)£20ppm<20ppmRelatedsubstances(In-houseHPLCmethod)Ascomycin£0.8%0.064%Dihydrotacrolimus£0.6%0.089%Totalimpurities£1.5%0.15%Residualsolvents(In-housemethod)Acetone£2000ppmNotdetectedEthanol£2000ppmNotdetectedAssay(onanhydrousbasis)98.0%~102.0%100.0%Conclusion:CompliedwithIn-Housestandard
