... of many trees,leaves of tea, fruits, nuts and seeds of many plants such as grape(Vitis vinifera L.), apple ... antioxidant, anti-inflammatory, cardioprotective, anti-tumoural, and antigenotoxic.Grape seeds proanthocyanidins (GSPs) have appeared on the market as nutritional supplements ... extractboth in vitro and in vivo. Pas extracted from grape seeds were found to be non- mutagenic, non-clastogenic and ...