... Both naringenin and hesperetin, which are the aglycones of naringin and hesperidin, occur naturally in citrus fruits.[edit] ... grapefruit) and other juices with medications is contraindicated. [2]Naringin, followed by rutin, was the most potent flavonoid inhibitor ... base, and then catalytically hydrogenated, it becomes a naringin dihydrochalcone, a compound roughly 300-1800 times sweeter than ...